Article
Lys656Asn polymorphism of leptin receptor, leptin levels and insulin resistance in patients with non alcoholic fatty liver disease.
European review for medical and pharmacological sciences - 1 Mar 2012
Aller R, De Luis D A, Izaola O, González Sagrado M, Conde R, Pacheco D, Velasco M C, Ovalle H F
Abstract excerpt
BACKGROUND: Some studies have pointed to a role of leptin and insulin resistance in pathogenesis of non alcoholic fatty liver disease (NAFLD). The aim of our study was to investigate the influence of Lys656Asn polymorphism LEPR gene on the histological changes, insulin resistance and leptin levels in overweight patients. MATERIAL AND METHODS: A population of 76 patients with NAFLD was recruited in a cross...
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