Article
Association between LIN28B gene polymorphisms and Wilms' tumor susceptibility.
Biomarkers in medicine - 1 Oct 2022
Zhang Zhengtao, Gao Xiaofeng, Deng Linqing, Jia Wei, Zhang Jiao, Cheng Jiwen, Zhou Haixia, Liu Guochang, Fu Wen
Abstract excerpt
Aim: To survey the association between LIN28B gene polymorphisms and the increased risk of Wilms' tumor (WT). Methods: Five LIN28B polymorphisms (rs314276 C>A, rs221634 A>T, rs221635 T>C, the rs4145418 A>C and rs9404590 T>G) were genotyped in 355 WT patients and 1070 healthy controls to assess the association. Result: The CA/AA genotype was a protective factor against WT (corrected odds ratio [OR]:...