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Targeted RNA‐sequencing assays: a step forward compared to FISH and IHC techniques?

25 Oct 2019

Abstract excerpt

Abstract Introduction ALK and ROS1 rearrangements are molecular targets of several tyrosine kinase inhibitors. RNA‐sequencing approaches are regarded as the new standard for fusion gene detection, representing an alternative to standard immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH) techniques. Patients and Methods We aimed to compare two recent amplicon‐based RNA‐sequencing techniques:...

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PMID: 31651105
DOI: 10.1002/cam4.2599

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