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Article

Investigation on the hereditary basis of colorectal cancers in an African population with frequent early onset cases.

PloS one - 1 Jan 2019

Katsidzira Leolin, Vorster Anna, Gangaidzo Innocent T, Makunike-Mutasa Rudo, Govender Dhiren, Rusakaniko Simbarashe, Thomson Sandie, Matenga Jonathan A, Ramesar Raj

Abstract excerpt

BACKGROUND: Approximately 25% of colorectal cancer patients in sub-Saharan Africa are younger than 40 years, and hereditary factors may contribute. We investigated the frequency and patterns of inherited colorectal cancer among black Zimbabweans. METHODS: A population-based cross-sectional study of ninety individuals with a new diagnosis of colorectal cancer was carried out in Harare, Zimbabwe between November...

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PMID: 31647837
DOI: 10.1371/journal.pone.0224023
PMCID: PMC6812839

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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