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Article

DNA polymerases in the risk and prognosis of colorectal and pancreatic cancers.

Mutagenesis - 19 Dec 2019

Silvestri Roberto, Landi Stefano

Abstract excerpt

Human cancers arise from the alteration of genes involved in important pathways that mainly affect cell growth and proliferation. DNA replication and DNA damages recognition and repair are among these pathways and DNA polymerases that take part in these processes are frequently involved in cancer onset and progression. For example, damaging alterations within the proofreading domain of replicative polymerases,...

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Identifiers

PMID: 31647559
DOI: 10.1093/mutage/gez031

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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