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Article

Identification of Rare Noncoding Variants in Familial Nonmedullary Thyroid Carcinoma.

Thyroid : official journal of the American Thyroid Association - 1 Feb 2026

Comiskey Daniel F, Liyanarachchi Sandya, Wu Joyce, Sheikh Mehek S, Hendrickson Isabella V, Brock Pamela L, Ringel Matthew D, Nieminen Taina T

Abstract excerpt

BACKGROUND: Familial nonmedullary thyroid carcinoma (FNMTC) occurs when three or more family members are affected by usually papillary thyroid carcinoma (PTC), the most common form of NMTC. While the heritability to NMTC is among the highest of all cancers, the genetic determinants among NMTC families are not well understood. Here, we aim to understand the contribution of rare noncoding germline variants in the...

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PMID: 41589591
DOI: 10.1177/10507256251408827

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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