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Article

C14orf93 (RTFC) is identified as a novel susceptibility gene for familial nonmedullary thyroid cancer.

Biochemical and biophysical research communications - 22 Jan 2017

Liu Chang, Yu Yang, Yin Guangliang, Zhang Junxia, Wen Wei, Ruan Xianhui, Li Dapeng, Zhang Shuang, Cai Wenjun, Gao Ming, Chen Lingyi

Abstract excerpt

The genetic causes for familial nonmedullary thyroid cancer (FNMTC) remain largely unknown. Through genetic linkage analysis and exome sequencing, C14orf93 (RTFC), PYGL, and BMP4 were identified as susceptibility gene candidates in a FNMTC family. By examining the expression and the oncogenic functions of these candidate genes, PYGL and BMP4 were excluded. We further characterized the functions of the...

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Source

Identifiers

PMID: 27864143
DOI: 10.1016/j.bbrc.2016.11.078

Genes

BMP4
PYGL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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