Article
No association of psychosis in Alzheimer disease with neurodegenerative pathway genes.
Neurobiology of aging - 1 Mar 2011
DeMichele-Sweet Mary Ann A, Klei Lambertus, Devlin Bernie, Ferrell Robert E, Weamer Elise A, Emanuel James E, Lopez Oscar L, Sweet Robert A
Abstract excerpt
Psychotic symptoms occur in approximately 40% of subjects with Alzheimer disease (AD with psychosis; AD + P) and identify a subgroup with more rapid cognitive decline. We evaluated in 867 AD subjects the association of AD + P with genes which may modify the pathological process via effects on the accumulation of amyloid beta (Aβ) protein and/or hyperphosphorylated microtubule-associated protein tau (MAPT):...
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