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Article

Avian interspecific differences in VKOR activity and inhibition: Insights from amino acid sequence and mRNA expression ratio of VKORC1 and VKORC1L1.

Comparative biochemistry and physiology. Toxicology & pharmacology : CBP - 1 Feb 2020

Nakayama Shouta M M, Morita Ayuko, Ikenaka Yoshinori, Kawai Yusuke K, Watanabe Kensuke P, Ishii Chihiro, Mizukawa Hazuki, Yohannes Yared B, Saito Keisuke, Watanabe Yukiko, Ito Masaki, Ohsawa Natsuo, Ishizuka Mayumi

Abstract excerpt

Worldwide use of anticoagulant rodenticides (ARs) for rodents control has frequently led to secondary poisoning of non-target animals, especially raptors. In order to suggest some factors that may help considering the mechanism of the incidents, this study focused on the avian vitamin K 2, 3-epoxide reductase (VKOR) that is the target protein of ARs. We addressed the interspecific differences in VKOR activity and...

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Identifiers

PMID: 31639498
DOI: 10.1016/j.cbpc.2019.108635

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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