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Article

Distribution of non-synonymous Vkorc1 mutations in roof rats (Rattus rattus) in France and in Spain - consequences for management.

Pesticide biochemistry and physiology - 1 May 2022

Damin-Pernik Marlène, Hammed Abdessalem, Giraud Ludivine, Goulois Joffrey, Benoît Etienne, Lattard Virginie

Abstract excerpt

Rodent control is mainly done using anticoagulant rodenticides leading to the death of rodents through internal bleeding by targeting the VKORC1 protein. However, mutations in VKORC1 can lead to resistance to anticoagulant rodenticides that can cause treatment failure in the field. This study provides the first insight into the distribution, frequency and characterization of Vkorc1 mutations in roof rats (Rattus...

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PMID: 35430058
DOI: 10.1016/j.pestbp.2022.105052

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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