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Article

The Molecular Mechanism of Epithelial–Mesenchymal Transition for Breast Carcinogenesis

11 Sept 2019

Abstract excerpt

The transforming growth factor-β (TGF-β) signaling pathway plays multiple regulatory roles in the tumorigenesis and development of cancer. TGF-β can inhibit the growth and proliferation of epithelial cells and induce apoptosis, thereby playing a role in inhibiting breast cancer. Therefore, the loss of response in epithelial cells that leads to the inhibition of cell proliferation due to TGF-β is a landmark event...

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PMID: 31514467
DOI: 10.3390/biom9090476

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