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Article

Comparing a few SNP calling algorithms using low-coverage sequencing data.

BMC bioinformatics - 17 Sept 2013

Yu Xiaoqing, Sun Shuying

Abstract excerpt

BACKGROUND: Many Single Nucleotide Polymorphism (SNP) calling programs have been developed to identify Single Nucleotide Variations (SNVs) in next-generation sequencing (NGS) data. However, low sequencing coverage presents challenges to accurate SNV identification, especially in single-sample data. Moreover, commonly used SNP calling programs usually include several metrics in their output files for each...

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PMID: 24044377
DOI: 10.1186/1471-2105-14-274
PMCID: PMC3848615

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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