Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Oncogenic Role of Secreted Engrailed Homeobox 2 (EN2) in Prostate Cancer

6 Sept 2019

Abstract excerpt

Engrailed variant-2 (EN2) has been suggested as a potential diagnostic biomarker; however, its presence and functional role in prostate cancer (PCa) cells is still controversial or unknown. Here, we analyzed 1) the expression/secretion profile of EN2 in five independent samples cohorts from PCa patients and controls (prostate tissues and/or urine) to determine its utility as a PCa biomarker; and 2) the functional...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related gene regulation
Share to Prostate Cancer Treatment and Research
Share to RNA Research and Splicing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31500112
DOI: 10.3390/jcm8091400

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Oncogenic Role of Secreted Engrailed Homeobox 2 (EN2) in Prostate CancerPMID 31500112Read ↗

Altered staining patterns and expression level of Engrailed-2 in Benign prostatic hyperplasia and Prostate Cancer predict Prostatic disease progressionSemantic proximity Read ↗

Role of Engrailed-2 (EN2) as a prostate cancer detection biomarker in genetically high risk menSemantic proximity Read ↗

Role of MicroRNAs in Neuroendocrine Prostate CancerSemantic proximity Read ↗

Importance of HOX genes in normal prostate gland formation, prostate cancer development and its early detectionSemantic proximity Read ↗

The Master Neural Transcription Factor BRN2 Is an Androgen Receptor–Suppressed Driver of Neuroendocrine Differentiation in Prostate CancerSemantic proximity Read ↗

SHOX2 promotes prostate cancer proliferation and metastasis through disruption of the Hippo-YAP pathwaySemantic proximity Read ↗

Unveiling potential: urinary exosomal mRNAs as non-invasive biomarkers for early prostate cancer diagnosisSemantic proximity Read ↗

Transcriptional network involving ERG and AR orchestrates Distal-less homeobox-1 mediated prostate cancer progressionSemantic proximity Read ↗

Androgen-regulated transcription of ESRP2 drives alternative splicing patterns in prostate cancerSemantic proximity Read ↗

Iroquois homeobox 4 (IRX4) derived micropeptide promotes prostate cancer progression and chemoresistance through Wnt signalling dysregulationSemantic proximity Read ↗

Neuropilin-2 axis in regulating secretory phenotype of neuroendocrine-like prostate cancer cells and its implication in therapy resistance.Semantic proximity Read ↗

Gene Expression Signature Predictive of Neuroendocrine Transformation in Prostate AdenocarcinomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.