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Article

Role of Engrailed-2 (EN2) as a prostate cancer detection biomarker in genetically high risk men

24 Jun 2013

Abstract excerpt

Controversy surrounds the use of PSA as a biomarker for prostate cancer detection, leaving an unmet need for a novel biomarker in this setting; urinary EN2 may identify individuals with clinically relevant prostate cancer. Male BRCA1 and BRCA2 mutation carriers are at increased risk of clinically significant prostate cancer and may benefit from screening. Urine samples from 413 BRCA1 and BRCA2 mutation carriers...

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Share to Bladder and Urothelial Cancer Treatments
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PMID: 23792811
DOI: 10.1038/srep02059

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