Article
Unveiling potential: urinary exosomal mRNAs as non-invasive biomarkers for early prostate cancer diagnosis
1 Aug 2024
Abstract excerpt
BACKGROUND: This study investigated the use of urinary exosomal mRNA as a potential biomarker for the early detection of prostate cancer (PCa). METHODS: Next-generation sequencing was utilized to analyze exosomal RNA from 10 individuals with confirmed PCa and 10 individuals without cancer. Subsequent validation through qRT-PCR in a larger sample of 43 PCa patients and 92 healthy controls revealed distinct mRNA...
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