Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Importance of HOX genes in normal prostate gland formation, prostate cancer development and its early detection

5 Jun 2013

Abstract excerpt

The aims of this paper were to review the published literature on the role of HOX genes in the development of the normal prostate gland and in prostate cancer and to discuss the potential role of the HOX family member, Engrailed-2 (EN2), as a diagnostic test of PCa. Hox genes were first described in the fruit fly Drosphila melanogaster, where they specify the body plan and control the formation of body segments....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Share to Prostate Cancer Treatment and Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 23937390
DOI: 10.1111/bju.12269

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Importance of HOX genes in normal prostate gland formation, prostate cancer development and its early detectionPMID 23937390Read ↗

Oncogenic Role of Secreted Engrailed Homeobox 2 (EN2) in Prostate CancerSemantic proximity Read ↗

Neuroendocrine prostate cancer has distinctive, non-prostatic HOX code that is represented by the loss of HOXB13 expressionSemantic proximity Read ↗

HOXB13 and other high penetrant genes for prostate cancer.Semantic proximity Read ↗

Altered staining patterns and expression level of Engrailed-2 in Benign prostatic hyperplasia and Prostate Cancer predict Prostatic disease progressionSemantic proximity Read ↗

Deregulation of a Hox Protein Regulatory Network Spanning Prostate Cancer Initiation and ProgressionSemantic proximity Read ↗

Role of Engrailed-2 (EN2) as a prostate cancer detection biomarker in genetically high risk menSemantic proximity Read ↗

HOXB13 mutations and binding partners in prostate development and cancer: Function, clinical significance, and future directionsSemantic proximity Read ↗

HOXD13 suppresses prostate cancer metastasis and BMP4 ‐induced epithelial‐mesenchymal transition by inhibiting SMAD1Semantic proximity Read ↗

MEIS-mediated suppression of human prostate cancer growth and metastasis through HOXB13-dependent regulation of proteoglycansSemantic proximity Read ↗

Essential roles of epithelial bone morphogenetic protein signaling during prostatic development.Semantic proximity Read ↗

Development of the human prostateSemantic proximity Read ↗

EXPRESSION OF THE DEVELOPMENTAL AND ONCOGENIC PAX2 GENE IN HUMAN PROSTATE CANCERSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.