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Hepatitis B virus–host interactions and novel targets for viral cure

22 May 2021

Abstract excerpt

Chronic infection with HBV is a major cause of advanced liver disease and hepatocellular carcinoma. Nucleos(t)ide analogues effectively control HBV replication but viral cure is rare. Hence treatment has often to be administered for an indefinite duration, increasing the risk for selection of drug resistant virus variants. PEG-interferon-α-based therapies can sometimes cure infection but suffer from a low...

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PMID: 34029994
DOI: 10.1016/j.coviro.2021.04.009

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