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Article

Clonal evolution of acute myeloid leukemia highlighted by latest genome sequencing studies.

Oncotarget - 6 Sept 2016

Zhang Xuehong, Lv Dekang, Zhang Yu, Liu Quentin, Li Zhiguang

Abstract excerpt

Decades of years might be required for an initiated cell to become a fully-pledged, metastasized tumor. DNA mutations are accumulated during this process including background mutations that emerge scholastically, as well as driver mutations that selectively occur in a handful of cancer genes and confer the cell a growth advantage over its neighbors. A clone of tumor cells could be superseded by another clone that...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 27474172
DOI: 10.18632/oncotarget.10850
PMCID: PMC5295455

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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