Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of key genes and pathways involved in microsatellite instability in colorectal cancer

11 Jan 2019

Abstract excerpt

Microsatellite instability (MSI) has emerged as one of the key biological features of colorectal cancer (CRC). However, controversies remain regarding the association between the MSI status and clinicopathological characteristics of CRC. Therefore, it is crucial to identify potential key genes and pathways associated with MSI in CRC. In the present study, the GSE25071 gene expression profile was retrieved, with...

Topics

Join the communities discussing this publication.

Colorectal Cancer Treatments and Studies
Ferroptosis and cancer prognosis
Genetic factors in colorectal cancer

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 30664178
DOI: 10.3892/mmr.2019.9849

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of key genes and pathways involved in microsatellite instability in colorectal cancerPMID 30664178Read ↗

Transcriptome and Network Dissection of Microsatellite Stable and Highly Instable Colorectal CancerSemantic proximity Read ↗

Gene expression differences among different MSI statuses in colorectal cancer.Semantic proximity Read ↗

CRC genome-driven metabolic reprogramming and immune microenvironment remodelingSemantic proximity Read ↗

Identification of hub genes and potential molecular mechanisms in MSS/MSI classifier primary colorectal cancer based on multiple datasetsSemantic proximity Read ↗

Glutathione peroxidase 2: A key factor in the development of microsatellite instability in colon cancerSemantic proximity Read ↗

Development and validation of novel proliferation-related gene signature for MSS colorectal cancer prognosisSemantic proximity Read ↗

mRNA/microRNA gene expression profile in microsatellite unstable colorectal cancerSemantic proximity Read ↗

The significance of microsatellite instability in colorectal cancer after controlling for clinicopathological factorsSemantic proximity Read ↗

Microsatellite instability in mismatch repair proficient colorectal cancer: clinical features and underlying molecular mechanisms.Semantic proximity Read ↗

DNA Copy-Number Alterations Underlie Gene Expression Differences between Microsatellite Stable and Unstable Colorectal CancersSemantic proximity Read ↗

MSICKB: A Curated Knowledgebase for Exploring Molecular Heterogeneity and Biomarker Discovery in Microsatellite Instability CancersSemantic proximity Read ↗

A mitophagy-related gene signature associated with prognosis and immune microenvironment in colorectal cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.