Article

Development and validation of novel proliferation-related gene signature for MSS colorectal cancer prognosis

2024-11-18

Abstract excerpt

Colorectal cancer (CRC) is classified into microsatellite instability (MSI) and microsatellite stabilized (MSS) based on the differences in DNA repair mechanisms. In recent years, many studies have proved that some emerging therapeutic approaches have good therapeutic effects on MSI as a subtype but are ineffective for MSS as a subtype. This paper aims to start with the molecular mechanism of MSS and try to find t...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 72338aae-9de8-5239-8a87-92c3b61e70f0
DOI: 10.1101/2024.11.13.623354

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Development and validation of novel proliferation-related gene signature for MSS colorectal cancer prognosisDOI 10.1101/2024.11.13.623354Read

Gene expression differences among different MSI statuses in colorectal cancer.Semantic proximity Read

Transcriptome and Network Dissection of Microsatellite Stable and Highly Instable Colorectal CancerSemantic proximity Read

The next bastion to be conquered in immunotherapy: microsatellite stable colorectal cancerSemantic proximity Read

Identification of key genes and pathways involved in microsatellite instability in colorectal cancerSemantic proximity Read

An Update on the Potential Roles of E2F Family Members in Colorectal CancerSemantic proximity Read

Clinical Retrospective Analysis: Higher Rates of Gene Mutations in the Microsatellite Stable (MSS) Population of Colorectal CancerSemantic proximity Read

DNA Mismatch Repair Deficiency Detection in Colorectal Cancer by a New Microsatellite Instability Analysis System.Semantic proximity Read

CRC genome-driven metabolic reprogramming and immune microenvironment remodelingSemantic proximity Read

Comparison of the differentially enriched mutations/pathways between stage II and stage IV dMMR/MSI-H colorectal cancer.Semantic proximity Read

Construction and evaluation of a prognostic risk model of DNA mismatch repair related genes in colorectal cancerSemantic proximity Read

Comprehensive analysis of gene mutations and mismatch repair in Chinese colorectal cancer patientsSemantic proximity Read

Microsatellite instability: a review of what the oncologist should knowSemantic proximity Read