Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association Between Pigmentation Heritage and Susceptibility to Experimentally Induced Myopia: Crossbreeding Insights From Albino and Pigmented Guinea Pigs.

Investigative ophthalmology & visual science - 2 Sept 2025

Jiang Liqin, Dan Yee Shan, Myles William E, Seah Sherlyn H Y, Koh James H Z, Khine Myo Thu, Schmetterer Leopold, Barathi Veluchamy A, Hoang Quan V

Abstract excerpt

Purpose: To investigate how pigmentation heritage affects susceptibility to form deprivation myopia (FDM) through crossbreeding myopia-susceptible albino and myopia-resistant pigmented guinea pigs (GPs). Methods: Ninety GPs (albino: n = 29, pigmented: n = 29, F1 crossbred: n = 32) were studied. Eye parameters were measured using retinoscopy and A-scan ultrasound. Scotopic electroretinograms were recorded by...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Albinism, Ocular
Share to Choroid

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Electroretinography

Share to Guinea Pigs

Share to Melanins

Share to Monophenol Monooxygenase

Share to Myopia

Share to Tomography, Optical Coherence

Source

Open in PubMed Open full text

Identifiers

PMID: 40970666
DOI: 10.1167/iovs.66.12.47
PMCID: PMC12453062

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 16 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association Between Pigmentation Heritage and Susceptibility to Experimentally Induced Myopia: Crossbreeding Insights From Albino and Pigmented Guinea Pigs.PMID 40970666Read ↗

Establishment and comprehensive characterization of a novel dark-reared zebrafish model for myopia studiesSemantic proximity Read ↗

Establishment and comprehensive characterization of a novel dark-reared zebrafish model for myopia studiesSemantic proximity Read ↗

The albino chick as a model for studying ocular developmental anomalies, including refractive errors, associated with albinism.Semantic proximity Read ↗

Genetic contributions to myopic refractive error: Insights from human studies and supporting evidence from animal modelsSemantic proximity Read ↗

Animal modeling for myopiaSemantic proximity Read ↗

[Pathophysiology of myopia: nature versus nurture].Semantic proximity Read ↗

A slc38a8 mouse model of FHONDA syndrome faithfully recapitulates the visual deficits of albinism without pigmentation defectsSemantic proximity Read ↗

The role of the retinal pigment epithelium: Topographical variation and ageing changesSemantic proximity Read ↗

Generation and ophthalmological characterization of oculocutaneous albinism type 1 pig models by selection-free genome editing.Semantic proximity Read ↗

Richer color experience in observers with multiple photopigment opsin genes.Semantic proximity Read ↗

Pigmentation and Retinal Pigment Epithelium Thickness: A Study of the Phenotypic and Genotypic Relationships Between Ocular and Extraocular Pigmented Tissues.Semantic proximity Read ↗

Influence of eye pigmentation on retinal degeneration in P23H and S334ter mutant rhodopsin transgenic rats.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.