Article
Susceptibility to retinal light damage in transgenic rats with rhodopsin mutations.
Investigative ophthalmology & visual science - 1 Feb 2003
Organisciak Daniel T, Darrow Ruth M, Barsalou Linda, Kutty R Krishnan, Wiggert Barbara
Abstract excerpt
PURPOSE: To determine relative light-induced retinal damage susceptibility in transgenic rats expressing mutations in the N- or C-terminal region of rhodopsin. METHODS: Heterozygous transgenic rats, including P23H sublines 2 and 3 and S334ter sublines 4 and 9, were reared in dim cyclic light or in darkness before visible light exposure starting at various times of the day or night. Before exposure to light, some...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
