Article
P23H and S334ter opsin mutations: Increasing photoreceptor outer segment n-3 fatty acid content does not affect the course of retinal degeneration.
Molecular vision - 26 Mar 2004
Martin Rex E, Ranchon-Cole Isabelle, Brush Richard S, Williamson Clint R, Hopkins Steven A, Li Feng, Anderson Robert E
Abstract excerpt
PURPOSE: The n-3 polyunsaturated fatty acids (PUFA) facilitate retinal development and function. Rats carrying transgenes with P23H and S334ter rhodopsin mutations lose their photoreceptors and have lower levels of 22:6n-3 in rod photoreceptor outer segments (ROS) than wild type (WT) animals. We...
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