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Genetic model of MS severity predicts future accumulation of disability

8 Aug 2019

Abstract excerpt

No genetic modifiers of multiple sclerosis (MS) severity have been independently validated, leading to a lack of insight into genetic determinants of the rate of disability progression. We investigated genetic modifiers of MS severity in prospectively acquired training (N = 205) and validation (N = 94) cohorts, using the following advances: (1) We focused on 113 genetic variants previously identified as related...

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PMID: 31396954
DOI: 10.1111/ahg.12342

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