Genetic predictors of chemotherapy-related amenorrhea in women with breast cancer.

doi:10.1016/j.fertnstert.2019.05.018

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Article

Genetic predictors of chemotherapy-related amenorrhea in women with breast cancer.

Fertility and sterility - 1 Oct 2019

Ruddy Kathryn J, Schaid Daniel J, Partridge Ann H, Larson Nicholas B, Batzler Anthony, Häberle Lothar, Dittrich Ralf, Widschwendter Peter, Fink Visnja, Bauer Emanuel, Schwitulla Judith, Rübner Matthias, Ekici Arif B, Aivazova-Fuchs Viktoria, Stewart Elizabeth A, Beckmann Matthias W, Ginsburg Elizabeth, Wang Liewei, Weinshilboum Richard M, Couch Fergus J, Janni Wolfgang, Rack Brigitte, Vachon Celine, Fasching Peter A

Abstract excerpt

OBJECTIVE: To study how genetics may play a role in determining risk of chemotherapy-related amenorrhea (CRA) in young women with breast cancer. DESIGN: Genome-wide association study. SETTING: Not applicable. PATIENT(S): Premenopausal women ≤45 years of age enrolled in one of these three trials were included if they had at least one menstrual case report form after chemotherapy ended and if they were of European...

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PMID: 31371054
DOI: 10.1016/j.fertnstert.2019.05.018
PMCID: PMC6765404

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