Article

Genetic prediction of long-term effects of aromatase inhibition on cancer and non-neoplastic disease risk

2026-04-29

Abstract excerpt

<h4>Background</h4> Anastrozole, an aromatase inhibitor, is approved for breast cancer prevention in high-risk women. The long-term effects of aromatase inhibition, including its repurposing potential to other cancers, possible adverse effects, and treatment effect heterogeneity across patient subgroups, remain unclear. <h4>Methods</h4> We used the rs727479 variant in CYP19A1 to mimic the effect of long-term ph...

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Literature Corpus work: fd68a7b2-2e43-53a1-86a5-bf269b711617
DOI: 10.64898/2026.04.28.26351848

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