Article
Chemotherapy-induced amenorrhea in patients with breast cancer with a BRCA1 or BRCA2 mutation.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 1 Nov 2013
Valentini Adriana, Finch Amy, Lubinski Jan, Byrski Tomasz, Ghadirian Parviz, Kim-Sing Charmaine, Lynch Henry T, Ainsworth Peter J, Neuhausen Susan L, Greenblatt Ellen, Singer Christian, Sun Ping, Narod Steven A
Abstract excerpt
PURPOSE: To determine the likelihood of long-term amenorrhea after treatment with chemotherapy in women with breast cancer who carry a BRCA1 or BRCA2 mutation. PATIENTS AND METHODS: We conducted a multicenter survey of 1,954 young women with a BRCA1 or BRCA2 mutation who were treated for breast cancer. We included premenopausal women who were diagnosed with invasive breast cancer between 26 and 47 years of age....
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