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Genetic Abnormalities and Challenges in the Treatment of Acute Myeloid Leukemia

1 Feb 2011

Abstract excerpt

Acute myeloid leukemia (AML) is a hematopoietic disorder in which there are too many immature blood-forming cells accumulating in the bone marrow and interfering with the production of normal blood cells. It has long been recognized that AML is a clinically heterogeneous disease characterized by a multitude of chromosomal abnormalities and gene mutations, which translate to marked differences in responses and...

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PMID: 21779483
DOI: 10.1177/1947601911408076

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