Article

Prevalence of Mendelian kidney disease among patients with high-risk<i>APOL1</i>genotypes undergoing commercial genetic testing in the United States

2024-02-14

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Among individuals with high-risk APOL1 genotypes, the lifetime risk of developing kidney failure is ∼15%, indicating that other genetic variants or non-genetic modifiers likely contribute substantially to an individual patient’s risk of progressive kidney disease. Here we estimate the prevalence and distribution of molecularly diagnosed Mendelian kidney diseases among patients...

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Literature Corpus work: 2e34b292-3135-5c93-bc00-d984516e6913
DOI: 10.1101/2024.02.13.24302777

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Prevalence of Mendelian kidney disease among patients with high-risk<i>APOL1</i>genotypes undergoing commercial genetic testing in the United StatesDOI 10.1101/2024.02.13.24302777Read

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