Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Article

The ORMDL3 asthma susceptibility gene regulates systemic ceramide levels without altering key asthma features in mice

20 Jul 2019

Abstract excerpt

No abstract is available from the source.

Topics

Join the communities discussing this publication.

Asthma and respiratory diseases
Sphingolipid Metabolism and Signaling
Spondyloarthritis Studies and Treatments

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 31330218
DOI: 10.1016/j.jaci.2019.06.041

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The ORMDL3 asthma susceptibility gene regulates systemic ceramide levels without altering key asthma features in micePMID 31330218Read ↗

Novel insights into in vivo functions of the asthma susceptibility gene ORMDL3Semantic proximity Read ↗

Childhood asthma is associated with mutations and gene expression differences of ORMDL genes that can interact.Semantic proximity Read ↗

Airway reactivity and sphingolipids—implications for childhood asthmaSemantic proximity Read ↗

From gene identifications to therapeutic targets for asthma: Focus on great potentials of TSLP, ORMDL3, and GSDMBSemantic proximity Read ↗

At last - linking ORMDL3 polymorphisms, decreased sphingolipid synthesis, and asthma susceptibility.Semantic proximity Read ↗

Sphingolipids and Asthma.Semantic proximity Read ↗

Sex hormones influence ORMDL3 expression: Implications for sex-associated asthma phenotype.Semantic proximity Read ↗

Oroscomucoid like protein 3 (ORMDL3) transgenic mice have reduced levels of sphingolipids including sphingosine-1-phosphate and ceramideSemantic proximity Read ↗

Pulmonary ORMDL3 is critical for induction of Alternaria-induced allergic airways diseaseSemantic proximity Read ↗

ORMDL3 expression levels have no influence on the activity of serine palmitoyltransferase.Semantic proximity Read ↗

Asthma Susceptibility Gene ORMDL3 Promotes Autophagy in Human Bronchial Epithelium.Semantic proximity Read ↗

Ceramide/sphingosine-1-phosphate imbalance is associated with distinct inflammatory phenotypes of uncontrolled asthma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.