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Article

The ORMDL3 asthma susceptibility gene regulates systemic ceramide levels without altering key asthma features in mice

20 Jul 2019

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Identifiers

PMID: 31330218
DOI: 10.1016/j.jaci.2019.06.041

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Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

The ORMDL3 asthma susceptibility gene regulates systemic ceramide levels without altering key asthma features in micePMID 31330218Read ↗

Novel insights into in vivo functions of the asthma susceptibility gene ORMDL3Semantic proximity Read ↗

Childhood asthma is associated with mutations and gene expression differences of ORMDL genes that can interact.Semantic proximity Read ↗

Airway reactivity and sphingolipids—implications for childhood asthmaSemantic proximity Read ↗

From gene identifications to therapeutic targets for asthma: Focus on great potentials of TSLP, ORMDL3, and GSDMBSemantic proximity Read ↗

At last - linking ORMDL3 polymorphisms, decreased sphingolipid synthesis, and asthma susceptibility.Semantic proximity Read ↗

Sphingolipids and Asthma.Semantic proximity Read ↗

Sex hormones influence ORMDL3 expression: Implications for sex-associated asthma phenotype.Semantic proximity Read ↗

Oroscomucoid like protein 3 (ORMDL3) transgenic mice have reduced levels of sphingolipids including sphingosine-1-phosphate and ceramideSemantic proximity Read ↗

Pulmonary ORMDL3 is critical for induction of Alternaria-induced allergic airways diseaseSemantic proximity Read ↗

ORMDL3 expression levels have no influence on the activity of serine palmitoyltransferase.Semantic proximity Read ↗

Asthma Susceptibility Gene ORMDL3 Promotes Autophagy in Human Bronchial Epithelium.Semantic proximity Read ↗

Ceramide/sphingosine-1-phosphate imbalance is associated with distinct inflammatory phenotypes of uncontrolled asthma.Semantic proximity Read ↗

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