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Article

Plasminogen and the Plasminogen Receptor, Plg-RKT, Regulate Macrophage Phenotypic, and Functional Changes.

Frontiers in immunology - 1 Jan 2019

Vago Juliana P, Sugimoto Michelle A, Lima Kátia M, Negreiros-Lima Graziele L, Baik Nagyung, Teixeira Mauro M, Perretti Mauro, Parmer Robert J, Miles Lindsey A, Sousa Lirlândia P

Abstract excerpt

Inflammation resolution is an active process that functions to restore tissue homeostasis. Clearance of apoptotic leukocytes by efferocytosis at inflammatory sites plays an important role in inflammation resolution and induces remarkable macrophage phenotypic and functional changes. Here, we investigated the effects of deletion of either plasminogen (Plg) or the Plg receptor, Plg-RKT, on the resolution of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 31316511
DOI: 10.3389/fimmu.2019.01458
PMCID: PMC6611080

Genes

CCL2
IL4
STAT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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