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Article

Research Techniques Made Simple: Using Genetic Variants for Randomization

20 Jun 2019

Abstract excerpt

Observational epidemiological studies have identified associations between a number of modifiable exposures and outcomes, including in dermatology, such as between smoking and psoriasis. However, it is challenging to determine if such relationships are causal because of the potential of confounding and reverse causation. Mendelian randomization (MR) is a statistical method that can be used to investigate the...

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PMID: 31230636
DOI: 10.1016/j.jid.2019.03.1138

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