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Article

Evolution of prodromal parkinsonian features in a cohort ofGBAmutation-positive individuals: a 6-year longitudinal study

20 Jun 2019

Abstract excerpt

Objectives GBA1mutations are a frequent risk factor for Parkinson disease (PD). The aim of this study is to evaluate clinical features in a group ofGBA1mutation–positive individuals over a 6-year follow-up. Methods This is a longitudinal study on a cohort ofGBA1-positive carriers. We enrolled 31 patients with Gaucher disease type 1 (GD), 29GBA1heterozygous carriers (HetGBAgroup) and 30 controls (HC) at baseline...

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PMID: 31221723
DOI: 10.1136/jnnp-2019-320394

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