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Article

A Comprehensive Assessment of Qualitative and Quantitative Prodromal Parkinsonian Features in Carriers of Gaucher Disease-Identifying Those at the Greatest Risk.

International journal of molecular sciences - 13 Oct 2022

Becker-Cohen Michal, Zimran Ari, Dinur Tama, Tiomkin Maayan, Cozma Claudia, Rolfs Arndt, Arkadir David, Shulman Elena, Manor Orly, Paltiel Ora, Yahalom Gilad, Berg Daniela, Revel-Vilk Shoshana

Abstract excerpt

Carriers of GBA1 gene variants have a significant risk of developing Parkinson’s disease (PD). A cohort study of GBA carriers between 40−75 years of age was initiated to study the presence of prodromal PD features. Participants underwent non-invasive tests to assess different domains of PD. Ninety-eight unrelated GBA carriers were enrolled (43 males) at a median age (range) of 51 (40−74) years; 71 carried the...

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Identifiers

PMID: 36293067
DOI: 10.3390/ijms232012211
PMCID: PMC9603254

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