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Article

The link between the GBA gene and parkinsonism.

The Lancet. Neurology - 1 Nov 2012

Sidransky Ellen, Lopez Grisel

Abstract excerpt

Mutations in the glucocerebrosidase (GBA) gene, which encodes the lysosomal enzyme that is deficient in Gaucher's disease, are important and common risk factors for Parkinson's disease and related disorders. This association was first recognised in the clinic, where parkinsonism was noted, albeit rarely, in patients with Gaucher's disease and more frequently in relatives who were obligate carriers. Subsequently,...

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Identifiers

PMID: 23079555
DOI: 10.1016/S1474-4422(12)70190-4
PMCID: PMC4141416

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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