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Article

Evolution of prodromal clinical markers of Parkinson disease in a GBA mutation-positive cohort.

JAMA neurology - 1 Feb 2015

Beavan Michelle, McNeill Alisdair, Proukakis Christos, Hughes Derralynn A, Mehta Atul, Schapira Anthony H V

Abstract excerpt

IMPORTANCE: Numerically, the most important genetic risk factor for the development of Parkinson disease (PD) is the presence of a glucocerebrosidase gene (GBA) mutation. OBJECTIVE: To evaluate longitudinally and clinically a GBA mutation-positive cohort and the evolution of the prodromal features of PD. DESIGN, SETTING, AND PARTICIPANTS: Participants in a study of the etiology and prodrome of PD were reevaluated...

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Identifiers

PMID: 25506732
DOI: 10.1001/jamaneurol.2014.2950
PMCID: PMC4326672

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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