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Article

Complement and its environmental determinants in the progression of human rheumatoid arthritis

15 Jun 2019

Abstract excerpt

Rheumatoid arthritis (RA) is a complex autoimmune disease with an etiology that is not yet well understood, disproportionally affects women and also varies in incidence and prevalence by population. The presence of anti-citrullinated protein antibodies (ACPA) is a highly specific biomarker for the diagnosis of clinically apparent RA. ACPA are also present in the serum for an average of 3-5 years prior to the...

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PMID: 31207549
DOI: 10.1016/j.molimm.2019.05.012

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