Article
The genetics of rheumatoid arthritis: risk and protection in different stages of the evolution of RA.
Rheumatology (Oxford, England) - 1 Feb 2016
Yarwood Annie, Huizinga Tom W J, Worthington Jane
Abstract excerpt
There is now a general consensus that RA has a spectrum of disease stages that can begin many years before the onset of clinical symptoms. It is widely thought that understanding the complex interplay between genetics and environment, and their role in pathogenesis, is essential in gaining further insight into the mechanisms that drive disease development and progression. More than 100 genetic susceptibility loci...
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