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Complement activation and regulation in rheumatic disease

1 Oct 2019

Abstract excerpt

Complement is a key component of the innate immune defence and in addition forms a bridge to the adaptive immune responses. As such complement is of vital importance for efficient protection against infections. However, the activity of the complement system can also aberrantly be directed against the tissues of the body itself and contribute to organ damage in a variety of diseases. In several rheumatic diseases...

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PMID: 31718864
DOI: 10.1016/j.smim.2019.101339

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