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Article

Mechanisms of disease: Genetic susceptibility and environmental triggers in the development of rheumatoid arthritis.

Nature clinical practice. Rheumatology - 1 Aug 2006

Klareskog Lars, Padyukov Leonid, Lorentzen Johnny, Alfredsson Lars

Abstract excerpt

Rheumatoid arthritis (RA) is a complex disease in which environmental agents are thought to interact with genetic factors that influence susceptibility. This interaction triggers immunologic events that eventually result in the clinical signs of arthritis. Knowledge of the chain of etiological events that lead to the development of RA is incomplete. In this review, we describe the experimental approaches that are...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16932734
DOI: 10.1038/ncprheum0249

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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