Article
Current concepts in the pathogenesis of early rheumatoid arthritis.
Best practice & research. Clinical rheumatology - 1 Feb 2009
Pratt Arthur G, Isaacs John D, Mattey Derek L
Abstract excerpt
Rheumatoid arthritis (RA) is a systemic inflammatory disease with a predilection for symmetrically distributed diarthroidal joints. It is clinically heterogeneous, with particular disease phenotypes defined according to a complex interplay of genes and the environment. In this chapter we first summarize current knowledge of RA genetic susceptibility, a field which has been transformed in recent years by powerful...
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