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Article

Complement, infection, and autoimmunity

13 Jun 2019

Abstract excerpt

PURPOSE OF REVIEW: Complement system dysfunction in terms of upregulation, downregulation, or dysregulation can create an imbalance of both host defense and inflammatory response leading to autoimmunity. In this review, we aimed at describing the role of complement system in host defense to inflection and in autoimmunity starting from the evidence from primary and secondary complement system deficiencies. RECENT...

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PMID: 31192812
DOI: 10.1097/bor.0000000000000633

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