CD43 sialoglycoprotein modulates cardiac inflammation and murine susceptibility to Trypanosoma cruzi infection.

doi:10.1038/s41598-019-45138-7

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Article

CD43 sialoglycoprotein modulates cardiac inflammation and murine susceptibility to Trypanosoma cruzi infection.

Scientific reports - 13 Jun 2019

Alisson-Silva Frederico, Mantuano Natália Rodrigues, Lopes Ana Luiza, Vasconcelos-Dos-Santos Andréia, Vale André Macedo, Costa Miriam Maria, Cannon Judy L, Oliveira Ana Carolina, Todeschini Adriane R

Abstract excerpt

CD43 (leukosialin) is a large sialoglycoprotein abundantly expressed on the surface of most cells from the hematopoietic lineage. CD43 is directly involved in the contact between cells participating in a series of events such as signaling, adherence and host parasite interactions. In this study we examined the role of CD43 in the immune response against Trypanosoma cruzi, the protozoan parasite that causes...

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PMID: 31197200
DOI: 10.1038/s41598-019-45138-7
PMCID: PMC6565700

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.