Article
A role for extracellular amastigotes in the immunopathology of Chagas disease.
Memorias do Instituto Oswaldo Cruz - 1 Jan 1999
Scharfstein J, Morrot A
Abstract excerpt
In spite of the growing knowledge obtained about immune control of Trypanosoma cruzi infection, the mechanisms responsible for the variable clinico-pathological expression of Chagas disease remain unknown. In a twist from previous concepts, recent studies indicated that tissue parasitism is a pre-requisite for the development of chronic myocarditis. This fundamental concept, together with the realization that T....
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