Article
Ex vivo T-lymphocyte chemokine receptor phenotypes in patients with chronic Chagas disease.
Revista da Sociedade Brasileira de Medicina Tropical - 1 Jan 2000
Miranda Matheus Barbosa de, Melo Adriene Siqueira de, Almeida Mariana Silva, Marinho Silvia Martins, Oliveira Wilson, Gomes Yara de Miranda
Abstract excerpt
INTRODUCTION: Elucidating the molecules involved in the inflammatory process of chronic Chagas disease may allow identification of treatment targets. METHODS: The ex vivo phenotypic expression of chemokine receptors CCR1, CCR3, CCR4, CCR5, CXCR2, CXCR3, CXCR4, and CXCR5 on the CD4+ and CD8+ T-cells of patients with chronic Chagas cardiomyopathy of varying severity was evaluated using flow cytometry. RESULTS:...
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