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Acute myeloid leukemia patient with FLT3-ITD and NPM1 double mutation should undergo allogeneic hematopoietic stem cell transplantation in CR1 for better prognosis

1 May 2019

Abstract excerpt

Background: According to the recent National Comprehensive Cancer Network (NCCN) guidelines, the risk level in acute myeloid leukemia (AML) patients with FLT3-ITD and NPM1 double mutation (AML FLT3-ITD+/NPM1+, ) depends on the allelic ratio of FLT3-ITD . But despite a low or high allelic ratio of FLT3-ITD , AML FLT3-ITD+/NPM1+, patients belong to the favorable or intermediate risk, for whom allogeneic stem cell...

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PMID: 31190985
DOI: 10.2147/cmar.s194523

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