Article
[Effect of FLT3-ITD with DNMT3A R882 double-mutation on the prognosis of acute myeloid leukemia after allogeneic hematopoietic stem cell transplantation].
Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi - 14 Jul 2018
Tang S H, Lu Y, Zhang P S, Liu X H, Du X H, Chen D, Sha K Y, Li S Y, Cao J J, Chen L G, Zhuang X X, Pei R Z, Tang X W
Abstract excerpt
Objective: To investigate the impact of FLT3-ITD and DNMT3A R882 double mutations to the prognosis of acute myeloid leukemia after allogeneic hematopoietic stem cell transplantation (allo-HSCT). Methods: FLT3-ITD, DNMT3A, C-kit, CEBPA, FLT3-TKD and NPM1 mutations were detected in 206 newly diagnosed AML patients by Sanger sequencing (M(3) and those received FLT3 inhibitor were excluded). Clinical data of AML...
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