FLT3-ITD Compared with DNMT3A R882 Mutation Is a More Powerful Independent Inferior Prognostic Factor in Adult Acute Myeloid Leukemia Patients After Allogeneic Hematopoietic Stem Cell Transplantation: A Retrospective Cohort Study

doi:10.4274/tjh.2018.0017

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FLT3-ITD Compared with DNMT3A R882 Mutation Is a More Powerful Independent Inferior Prognostic Factor in Adult Acute Myeloid Leukemia Patients After Allogeneic Hematopoietic Stem Cell Transplantation: A Retrospective Cohort Study

Turkish journal of haematology : official journal of Turkish Society of Haematology - 3 Aug 2018

Ardestani Majid Teremmahi, Kazemi Ahmad, Chahardouli Bahram, Mohammadi Saeed, Nikbakht Mohsen, Rostami Shahrbano, Jalili Mahdi, Vaezi Mohammad, Alimoghaddam Kamran, Ghavamzadeh Ardeshir

Abstract excerpt

Objective: This study aimed to evaluate DNMT3A exon 23 mutations and their prognostic impacts in the presence of NPM1 and FLT3 mutations in acute myeloid leukemia (AML) patients who underwent allogeneic hematopoietic stem cell transplantation (HSCT). Materials and Methods: This study comprised 128 adult AML patients referred to the Hematology-Oncology and Stem Cell Research Center of Shariati Hospital. NPM1 and...

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PMID: 29786546
DOI: 10.4274/tjh.2018.0017
PMCID: PMC6110452

Genes

FLT3
NPM1

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FLT3-ITD Compared with DNMT3A R882 Mutation Is a More Powerful Independent Inferior Prognostic Factor in Adult Acute Myeloid Leukemia Patients After Allogeneic Hematopoietic Stem Cell Transplantation: A Retrospective Cohort StudyPMID 29786546Read ↗

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