T-cell replete haploidentical stem cell transplantation attenuates the prognostic impact of FLT3-ITD in acute myeloid leukemia: A report from the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation.

doi:10.1002/ajh.25082

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Article

T-cell replete haploidentical stem cell transplantation attenuates the prognostic impact of FLT3-ITD in acute myeloid leukemia: A report from the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation.

American journal of hematology - 1 Jun 2018

Canaani Jonathan, Labopin Myriam, Huang Xiao-Jun, Arcese William, Ciceri Fabio, Blaise Didier, Irrera Giuseppe, Corral Lucia Lopez, Bruno Benedetto, Santarone Stella, Van Lint Maria Teresa, Vitek Antonin, Esteve Jordi, Mohty Mohamad, Nagler Arnon

Abstract excerpt

Acute myeloid leukemia (AML) patients harboring the FLT3-ITD mutation are considered a high risk patient subset preferentially allocated for allogeneic stem cell transplantation in first remission. Whether FLT3-ITD retains a prognostic role in haploidentical stem cell transplantation (haplo-SCT) is unknown. To analyze the prognostic impact of FLT3-ITD in haplo-SCT, we performed a retrospective analysis of the...

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PMID: 29498106
DOI: 10.1002/ajh.25082

Genes

FLT3
SCT
NPM1

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