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Prognostic impact of clinico-genetic characteristics and donor types in NPM1-mutated AML undergoing allogeneic hematopoietic stem cell transplantation.

Cell transplantation - 1 Jan 2026

Yuan Xiaolin, Wu Yibo, Yang Tingting, Zhu Panpan, Lai Xiaoyu, Liu Lizhen, Yang Luxin, Shi Jimin, Yu Jian, Zhao Yanmin, Zheng Weiyan, Sun Jie, Wu Wenjun, Zhao Yi, Cai Zhen, Huang He, Pei Shanshan, Luo Yi

Abstract excerpt

NPM1-mutated acute myeloid leukemia (AML) is a distinct entity with specific biological and clinicopathological features. Prognosis varies depending on the associated mutations and clinical characteristics. This study evaluated the prognostic factors of NPM1-mutated AML in patients who underwent allogeneic hematopoietic stem cell transplantation (allo-HSCT). We enrolled 139 patients with NPM1-mutated AML who...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41679976
DOI: 10.1177/09636897251414205
PMCID: PMC12901938

Genes

FLT3
NPM1
IDH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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